Old is new again: a chemical probe for targeting mitochondria and monitoring mitochondrial membrane potential in cells.
نویسندگان
چکیده
Here, we explore the new application of an old molecule. We find that the tetraphenylethene-indolium molecule (TPE-indo) can both image the mitochondria (in the aggregated state), and indicate mitochondrial activity by the fluorescence change of TPE-indo. TPE-indo shows good photostability, longer emission wavelength, targeting effect for mitochondria, and better response to the changes of the mitochondrial membrane potential (ΔΨm).
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ورودعنوان ژورنال:
- The Analyst
دوره 140 17 شماره
صفحات -
تاریخ انتشار 2015